Best practice portal – evidence database

This database gives you access to the latest evidence on drug-related interventions. The information is based on systematic searches is updated regularly. To get started use the search boxes below. Click here for more information about the Evidence database (including methods).

List of Evidence Summaries
Title Area Substance Target group(s) or setting(s) Evidence rating
Naltrexone to reduce criminal activity (re-incarceration) and improve treatment outcomes in drug-using offenders Harm reduction opioids prison Trade-off between benefits and harms
Psychosocial treatments for depression and substance use disorders Treatment co-morbidity dual-diagnosis patients Unknown effectiveness
Syringe provision through pharamcies, vending machines and mobile vans to reduce HIV, HCV and injecting risk behaviour Harm reduction amphetamines, opioids PWID – people who inject drugs Unknown effectiveness
Treatment of attention deficit hyperactivity disorder (ADHD) and substance use disorders in adolescents Treatment co-morbidity, not-drug specific dual-diagnosis patients Unknown effectiveness
Non-pharmacological interventions for deprescribing benzodiazepines and Z-drugs Treatment prescription medicines Unknown effectiveness
Shared decision-making tools to reduce substance use Treatment not-drug specific Unknown effectiveness
Behavioural harm reduction interventions to reduce HIV risk outcomes in crack/cocaine users Harm reduction cocaine Unknown effectiveness
Mentoring for preventing drug use in young people Prevention not-drug specific communities, young people Unknown effectiveness
Family- or individual-level multiple risk behaviour interventions to prevent illicit drug use Prevention not-drug specific young people Unknown effectiveness
Life skill and social influence–based interventions to reduce hard drug use Prevention opioids school Unknown effectiveness
Primary care models to improve opioid use disorders outcomes Treatment opioids communities Unknown effectiveness
Physical exercise to improve drug-related outcomes Treatment not-drug specific Unknown effectiveness
Pharmacological treatments for personality and substance use disorders Treatment co-morbidity dual-diagnosis patients Unknown effectiveness
Distribution of safer crack-use-paraphernalia to reduce crack-related harms Harm reduction cocaine Unknown effectiveness
Positive youth development (PYD) interventions to reduce substance use Prevention not-drug specific communities, young people Unknown effectiveness
Drug court programmes to improve employment outcomes Social reintegration not-drug specific prison Unknown effectiveness
Family- or individual-level multiple risk behaviour interventions to prevent cannabis use Prevention cannabis young people Unknown effectiveness
Universal school-based interventions to prevent multiple risk behaviours relating to alcohol, tobacco and drug use Prevention alcohol, cannabis, tobacco school Unknown effectiveness
Standalone life skill-based interventions to reduce hard drug use Prevention opioids school Unknown effectiveness
Pharmacological management of opium withdrawal Treatment opioids Unknown effectiveness
Integrated care of infectious diseases and substance use disorders to improve infectious disease treatment outcomes Treatment alcohol, co-morbidity, not-drug specific, amphetamines, cannabis, cocaine, new psychoactive substances (NPS), opioids, prescription medicines, tobacco communities, dual-diagnosis patients, emergency department, ethnic minority, families, law enforcement, pregnant women, PWID – people who inject drugs, school, women, prison, young people, partygoers/nightlife Unknown effectiveness
Police-based diversion measures to prevent drug use Harm reduction not-drug specific law enforcement Unknown effectiveness
Opioid withdrawal with antagonists under minimal sedation to retain patients and reduce relapses Treatment opioids Unknown effectiveness
Drug consumption rooms (DCRs) to reduce harms for homeless and vulnerably housed persons Harm reduction amphetamines, opioids PWID – people who inject drugs Unknown effectiveness
Workplace-based interventions for the prevention and treatment of problematic substance use Prevention Unknown effectiveness
Primary care behavioural interventions to prevent or reduce substance use in children and adolescents Prevention not-drug specific communities, young people Unknown effectiveness
Psycho-social treatment (including contingency management) to improve crack-cocaine users employment conditions Social reintegration cocaine Unknown effectiveness
Behavioural activation (BA) interventions to reduce substance use and depressive symptoms Treatment co-morbidity dual-diagnosis patients Unknown effectiveness
Targeted school-level interventions to prevent multiple risk behaviours relating to alcohol, tobacco and drug use Prevention alcohol, cannabis, tobacco school Unknown effectiveness
School-based generic prevention programs in preventing alcohol misuse in school-aged children up to 18 years of age Prevention alcohol school Unknown effectiveness
Community interventions to reduce harms from alcohol and other drug use Prevention alcohol, not-drug specific, cannabis communities Unknown effectiveness
Telemedicine-delivered treatment interventions for substance use disorders Treatment alcohol, opioids, tobacco communities, dual-diagnosis patients, emergency department, ethnic minority, families, law enforcement, pregnant women, PWID – people who inject drugs, school, women, prison, young people, partygoers/nightlife Unknown effectiveness
School-based eHealth interventions to prevent risk behaviours Prevention not-drug specific young people Unknown effectiveness
Opioid withdrawal for adolescent opioid users Treatment opioids young people Unknown effectiveness
Needle and syringe programmes in prison to prevent HIV and HCV infection and reduce injecting risk behaviours Harm reduction opioids prison Unknown effectiveness
Brief interventions delivered in general medical settings to reduce use and harms Treatment alcohol, cannabis Unknown effectiveness
Occupation-based interventions to improve recovery outcomes Social reintegration Unknown effectiveness
Cognitive-behavioural treatment (CBT) to reduce stimulant use Treatment amphetamines, cocaine Unknown effectiveness
Employer-led interventions to reduce use and adverse effects Social reintegration not-drug specific Unknown effectiveness
Family and individual-based interventions to prevent multiple risk behaviours relating to alcohol, tobacco and drug use Prevention alcohol, cannabis, tobacco families Unknown effectiveness
School-based brief interventions to reduce substance use and delinquent-type behaviours Prevention alcohol, cannabis school Unknown effectiveness
Neurostimulation techniques in the treatment of cocaine dependence Treatment cocaine Unknown effectiveness
Assertive community treatment (ACT) for substance use disorders Treatment alcohol, co-morbidity, not-drug specific, amphetamines, cannabis, cocaine, new psychoactive substances (NPS), opioids, prescription medicines, tobacco communities, dual-diagnosis patients, emergency department, ethnic minority, families, law enforcement, pregnant women, PWID – people who inject drugs, school, women, prison, young people, partygoers/nightlife Unknown effectiveness
Psychotherapy to improve mental and treatment outcomes in patients with comorbid bipolar and substance use disorders Treatment not-drug specific dual-diagnosis patients Unknown effectiveness
Brief interventions in patients with comorbid substance use Treatment co-morbidity Unknown effectiveness
Substitution treatment for adolescent opioid users Treatment opioids young people Unknown effectiveness
Pub-watching schemes to reduce alcohol-related crime against property Prevention alcohol law enforcement, partygoers/nightlife Unknown effectiveness
Opioid substitution treatment (OST) to prevent HIV and HCV in prison Harm reduction opioids prison Unknown effectiveness
Therapeutic communities to improve treatment outcomes Treatment not-drug specific Unknown effectiveness
Permanent supportive housing (specifically Housing First) to reduce harms Harm reduction, Social reintegration not-drug specific communities Unknown effectiveness

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