Opioid withdrawal with antagonists under minimal sedation to retain patients and reduce relapses

Summary of the evidence

Rating
  • Unknown effectiveness

In a systematic review (Gowing 2009, 4 RCTs, N=394), there was no significant difference in:

  • completion rate (RR 1.26, 95 % CI 0.80 to 2.00);
  • relapse to use rates (RR 0.83, 95 % CI 0.52 to 1.35).
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