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Opioid withdrawal with antagonists under minimal sedation to retain patients and reduce relapses
Summary of the evidence
In a systematic review (Gowing 2009, 4 RCTs, N=394), there was no significant difference in:
- completion rate (RR 1.26, 95 % CI 0.80 to 2.00);
- relapse to use rates (RR 0.83, 95 % CI 0.52 to 1.35).