Best practice portal – evidence database

This database gives you access to the latest evidence on drug-related interventions. The information is based on systematic searches is updated regularly. To get started use the search boxes below. Click here for more information about the Evidence database (including methods).

List of Evidence Summaries
Title Area Substance Target group(s) or setting(s) Evidence rating
Interventions to increase knowledge and reduce risk of drugs-and-driving Prevention alcohol, cannabis young people Likely to be beneficial
mHealth (mobile/wearable device) to reduce craving and use in substance use disorders Treatment not-drug specific Likely to be beneficial
Integrated approaches to improve engagement and adherence to HCV treatment among PWID Treatment opioids PWID – people who inject drugs Likely to be beneficial
Naloxone to revert synthetic opioids overdose Harm reduction new psychoactive substances (NPS), opioids, prescription medicines emergency department, PWID – people who inject drugs Likely to be beneficial
Interventions that lead to the highest treatment retention for young adults Treatment alcohol, cannabis, opioids young people Likely to be beneficial
Naltrexone to retain people in treatment Treatment opioids Likely to be beneficial
Combined enforcement checks and management training to reduce under-age serving Prevention alcohol law enforcement, partygoers/nightlife Likely to be beneficial
Computer-based treatment programs to improve mental health and treatment outcomes Treatment co-morbidity dual-diagnosis patients Likely to be beneficial
Drug court programmes to reduce recidivism Social reintegration not-drug specific prison Likely to be beneficial
Psychostimulants to reduce stimulant use Treatment amphetamines, cocaine Likely to be beneficial
Opioid substitution treatment (OST) to improve anti-retro-viral treatment in HIV positive opioid users Harm reduction opioids PWID – people who inject drugs Likely to be beneficial
Police-based diversion measures to prevent criminal offending and decrease social costs Harm reduction not-drug specific law enforcement Likely to be beneficial
Multi-substance interventions addressing tobacco and/or cannabis to reduce use Treatment cannabis, tobacco Likely to be beneficial
Psychosocial interventions for family members affected by substance abuse Treatment not-drug specific families Likely to be beneficial
Manualised mindfulness-based programs for substance use disorders to reduce cravings Treatment not-drug specific Likely to be beneficial
Contingency management for patients with psychotic and substance use disorders Treatment not-drug specific dual-diagnosis patients Likely to be beneficial
Therapeutic communities in prison to reduce re-incarceration rates and drug misuse relapse Treatment opioids prison Likely to be beneficial
Outreach and education to reduce injecting risk behaviour Harm reduction amphetamines, opioids PWID – people who inject drugs Likely to be beneficial
Behavioural therapies to reduce use in adolescents Treatment not-drug specific young people Likely to be beneficial
Training for alcohol servers to reduce the level of patron’s intoxication Prevention alcohol partygoers/nightlife Likely to be beneficial
Continuity of care to improve post-release behavioural outcomes Treatment not-drug specific prison Likely to be beneficial
Comprehensive family-oriented prevention for cannabis use Prevention cannabis families, young people Likely to be beneficial
Pre-exposure prophylaxis of HIV in adults at high risk (PreP) to reduce HIV acquisition Harm reduction amphetamines, opioids PWID – people who inject drugs Likely to be beneficial
Continuing care to improve treatment outcomes Treatment not-drug specific Likely to be beneficial
Anti-tobacco multi-component community interventions Prevention tobacco communities Likely to be beneficial
Community interventions to reduce risky drinking Prevention alcohol, not-drug specific communities Likely to be beneficial
Multidimensional family therapy (MDFT) vs cognitive behavioral therapy (CBT) to reduce use Treatment cannabis families, young people Likely to be beneficial
Family-based prevention programs in preventing alcohol misuse in school-aged children up to 18 years of age Prevention alcohol communities, young people Likely to be beneficial
Interactive programmes vs non interactive ones for problematic students use of licit and illicit drugs Prevention not-drug specific school Likely to be beneficial
Psychosocial interventions delivered to affected others of people with addictions Treatment not-drug specific families Likely to be beneficial
Antipsychotic treatment for schizophrenia and substance use disorders Treatment Likely to be beneficial
Alpha2-adrenergic agonists for the management of opioid withdrawal Treatment opioids Likely to be beneficial
Provision of injecting paraphenalia to reduce injecting risk behaviour Harm reduction amphetamines, opioids PWID – people who inject drugs Likely to be beneficial
Brief interventions to reduce alcohol use Treatment Likely to be beneficial
Internet-based interventions to reduce opiods use Treatment opioids Likely to be beneficial
Communities That Care (CTC) approach to prevent use and reduce youth problematic behaviours Prevention not-drug specific communities Likely to be beneficial
Case management to improve treatment outcomes Treatment not-drug specific Likely to be beneficial
School health services to reduce use Prevention alcohol, not-drug specific young people Likely to be beneficial
Opioid withdrawal with antagonists under heavy sedation to reduce adverse effects Treatment opioids Evidence of ineffectiveness
Information provision to prevent drug- and alcohol-related problems Prevention alcohol partygoers/nightlife Evidence of ineffectiveness
Educational interventions in recreational settings to influence attitudes and drinking behaviour Prevention alcohol partygoers/nightlife Evidence of ineffectiveness
Replacement of glassware in recreational settings aimed at preventing injuries among servers Prevention alcohol partygoers/nightlife Evidence of ineffectiveness
Electronic Age Verification (EAV) devices to increase the frequency of age verification at recreational premises Prevention alcohol partygoers/nightlife Evidence of ineffectiveness
Standalone mass-media campaigns for alcohol consumption Prevention alcohol partygoers/nightlife Evidence of ineffectiveness
Opioid withdrawal with antagonists under heavy sedation to retain patients and reduce use Treatment opioids Evidence of ineffectiveness
Compulsory drug treatment to reduce recidivism Treatment not-drug specific Evidence of ineffectiveness
Standalone mass-media campaign for tobacco consumption Prevention tobacco Evidence of ineffectiveness
Availability of take-home naloxone (THN) to increase opioid use Harm reduction opioids PWID – people who inject drugs Evidence of ineffectiveness
Drink-driving programmes to reduce alcohol-related injury in car crashes Prevention alcohol partygoers/nightlife Evidence of ineffectiveness
Farmacoterapia para mujeres embarazadas Treatment cannabis pregnant women Evidence of ineffectiveness
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